Phosphorylation and modulation of hyperpolarization-activated HCN4 channels by protein kinase A in the mouse sinoatrial node

The sympathetic nervous system increases heart rate by activating β adrenergic receptors and increasing cAMP levels in myocytes in the sinoatrial node. The molecular basis for this response is not well understood; however, the cardiac funny current (I(f)) is thought to be among the end effectors for...

Full description

Saved in:
Bibliographic Details
Main Authors: Liao, Zhandi, Lockhead, Dean, Larson, Eric D., Proenza, Catherine
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2931151/
https://ncbi.nlm.nih.gov/pubmed/20713547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201010488
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items