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Proteolytic Cleavage of Human Acid-sensing Ion Channel 1 by the Serine Protease Matriptase
Acid-sensing ion channel 1 (ASIC1) is a H(+)-gated channel of the amiloride-sensitive epithelial Na(+) channel (ENaC)/degenerin family. ASIC1 is expressed mostly in the central and peripheral nervous system neurons. ENaC and ASIC function is regulated by several serine proteases. The type II transme...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2010
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930712/ https://ncbi.nlm.nih.gov/pubmed/20601429 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153213 |
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