Two PKC consensus sites on human acid-sensing ion channel 1b differentially regulate its function

Human acid-sensing ion channel 1b (hASIC1b) is a H(+)-gated amiloride-sensitive cation channel. We have previously shown that glioma cells exhibit an amiloride-sensitive cation conductance. Amiloride and the ASIC1 blocker psalmotoxin-1 decrease the migration and proliferation of glioma cells. PKC al...

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Detalhes bibliográficos
Main Authors: Bashari, Edlira, Qadri, Yawar J., Zhou, Zhen-Hong, Kapoor, Niren, Anderson, Susan J., Meltzer, Robert H., Fuller, Catherine M., Benos, Dale J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2009
Assuntos:
Membrane Transporters, Ion Channels, and Pumps
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643847/
https://ncbi.nlm.nih.gov/pubmed/19091960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00200.2008
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