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Proteolytic Cleavage of Human Acid-sensing Ion Channel 1 by the Serine Protease Matriptase

Acid-sensing ion channel 1 (ASIC1) is a H(+)-gated channel of the amiloride-sensitive epithelial Na(+) channel (ENaC)/degenerin family. ASIC1 is expressed mostly in the central and peripheral nervous system neurons. ENaC and ASIC function is regulated by several serine proteases. The type II transme...

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Detalhes bibliográficos
Main Authors: Clark, Edlira B., Jovov, Biljana, Rooj, Arun K., Fuller, Catherine M., Benos, Dale J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930712/
https://ncbi.nlm.nih.gov/pubmed/20601429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.153213
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