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Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases

The epithelial extracellular membrane-associated serine proteases matriptase, hepsin, and prostasin are proteolytic modifying enzymes of the extracellular domain (ECD) of the epidermal growth factor receptor (EGFR). Matriptase also cleaves the ECD of the vascular endothelial growth factor receptor 2...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Chen, Li-Mei, Chai, Karl X.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593577/
https://ncbi.nlm.nih.gov/pubmed/28915606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17009
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