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Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases

Over three quarters of receptor tyrosine kinase (RTK) families are reported to have intracellular localization in response to environmental stimuli. Internalized RTK can bind to non-canonical substrates and affect various cellular processes. Many of the intracellular RTKs exist as fragmented forms t...

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Bibliographic Details
Published in:FEBS J
Main Authors: Chen, Mei-Kuang, Hung, Mien-Chie
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591179/
https://ncbi.nlm.nih.gov/pubmed/26096795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13342
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