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Proteolytic cleavage, trafficking, and functions of nuclear receptor tyrosine kinases

Over three quarters of receptor tyrosine kinase (RTK) families are reported to have intracellular localization in response to environmental stimuli. Internalized RTK can bind to non-canonical substrates and affect various cellular processes. Many of the intracellular RTKs exist as fragmented forms t...

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Bibliografiske detaljer
Udgivet i:FEBS J
Main Authors: Chen, Mei-Kuang, Hung, Mien-Chie
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4591179/
https://ncbi.nlm.nih.gov/pubmed/26096795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/febs.13342
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