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Proteolytic cleavages in the extracellular domain of receptor tyrosine kinases by membrane-associated serine proteases

The epithelial extracellular membrane-associated serine proteases matriptase, hepsin, and prostasin are proteolytic modifying enzymes of the extracellular domain (ECD) of the epidermal growth factor receptor (EGFR). Matriptase also cleaves the ECD of the vascular endothelial growth factor receptor 2...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Chen, Li-Mei, Chai, Karl X.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593577/
https://ncbi.nlm.nih.gov/pubmed/28915606
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17009
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