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MDM2 Mediates Ubiquitination and Degradation of Activating Transcription Factor 3
Activating transcription factor 3 (ATF3) is a common stress sensor, and its rapid induction by cellular stresses (e.g. DNA damage) is crucial for cells to mount appropriate responses (e.g. activating the tumor suppressor p53) and maintain homeostasis. Although emerging evidence suggests that dysregu...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930690/ https://ncbi.nlm.nih.gov/pubmed/20592017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.132597 |
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