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Ras-mediated activation of the TORC2–PKB pathway is critical for chemotaxis
In chemotactic cells, G protein–coupled receptors activate Ras proteins, but it is unclear how Ras-associated pathways link extracellular signaling to cell migration. We show that, in Dictyostelium discoideum, activated forms of RasC prolong the time course of TORC2 (target of rapamycin [Tor] comple...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Rockefeller University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2930282/ https://ncbi.nlm.nih.gov/pubmed/20660630 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201001129 |
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