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PIP3-independent activation of TorC2 and PKB at the cell’s leading edge mediates chemotaxis

BACKGROUND: Studies show that high phosphotidylinositol 3,4,5 tris phosphate (PIP(3)) promotes cytoskeletal rearrangements and alters cell motility and chemotaxis, possibly through activation of PKBs. However, chemotaxis can still occur in the absence of PIP(3) and the identities of the PIP(3) indep...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Kamimura, Yoichiro, Xiong, Yuan, Iglesias, Pablo A., Hoeller, Oliver, Bolourani, Parvin, Devreotes, Peter N.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: 2008
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018231/
https://ncbi.nlm.nih.gov/pubmed/18635356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.06.068
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