PIP3-independent activation of TorC2 and PKB at the cell’s leading edge mediates chemotaxis

BACKGROUND: Studies show that high phosphotidylinositol 3,4,5 tris phosphate (PIP(3)) promotes cytoskeletal rearrangements and alters cell motility and chemotaxis, possibly through activation of PKBs. However, chemotaxis can still occur in the absence of PIP(3) and the identities of the PIP(3) indep...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kamimura, Yoichiro, Xiong, Yuan, Iglesias, Pablo A., Hoeller, Oliver, Bolourani, Parvin, Devreotes, Peter N.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4018231/
https://ncbi.nlm.nih.gov/pubmed/18635356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.06.068
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker