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mTORC2 REGULATES NEUTROPHIL CHEMOTAXIS IN A cAMP- AND RhoA-DEPENDENT FASHION
We studied the role of the target of rapamycin complex 2 (mTORC2) during neutrophil chemotaxis, a process that is mediated through the polarization of actin and myosin filament networks. We show that inhibition of mTORC2 activity, achieved via knock down (KD) of Rictor, severely inhibits neutrophil...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071587/ https://ncbi.nlm.nih.gov/pubmed/21145500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.004 |
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