mTORC2 REGULATES NEUTROPHIL CHEMOTAXIS IN A cAMP- AND RhoA-DEPENDENT FASHION

We studied the role of the target of rapamycin complex 2 (mTORC2) during neutrophil chemotaxis, a process that is mediated through the polarization of actin and myosin filament networks. We show that inhibition of mTORC2 activity, achieved via knock down (KD) of Rictor, severely inhibits neutrophil...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Liu, Lunhua, Das, Satarupa, Losert, Wolfgang, Parent, Carole A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071587/
https://ncbi.nlm.nih.gov/pubmed/21145500
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.004
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi