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mTORC2 REGULATES NEUTROPHIL CHEMOTAXIS IN A cAMP- AND RhoA-DEPENDENT FASHION
We studied the role of the target of rapamycin complex 2 (mTORC2) during neutrophil chemotaxis, a process that is mediated through the polarization of actin and myosin filament networks. We show that inhibition of mTORC2 activity, achieved via knock down (KD) of Rictor, severely inhibits neutrophil...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071587/ https://ncbi.nlm.nih.gov/pubmed/21145500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2010.11.004 |
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