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Long distance communication in the HDV ribozyme: Insights from molecular dynamics and experiments

The hepatitis delta virus (HDV) ribozyme is a small self-cleaving RNA with a compact tertiary structure and buried active site that is important in the life cycle of the virus. The ribozyme’s function in nature is to cleave an internal phosphodiester bond and linearize concatemers during rolling cir...

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Bibliografiske detaljer
Main Authors: Veeraraghavan, Narayanan, Bevilacqua, Philip C., Hammes-Schiffer, Sharon
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2930087/
https://ncbi.nlm.nih.gov/pubmed/20643139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2010.07.025
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