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Functional studies of Plasmodium falciparum dipeptidyl aminopeptidase I (DPAP1) using small molecule inhibitors and active site probes

The widespread resistance of malaria parasites to all affordable drugs has made the identification of new targets urgent. Dipeptidyl aminopeptidases (DPAPs) represent potentially valuable new targets that are involved in hemoglobin degradation (DPAP1) and parasite egress (DPAP3). Here we use activit...

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書誌詳細
主要な著者: Deu, Edgar, Leyva, Melissa J., Albrow, Victoria E., Rice, Mark J., Ellman, Jonathan A., Bogyo, Matthew
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2929396/
https://ncbi.nlm.nih.gov/pubmed/20797610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.06.007
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