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Development of small molecule inhibitors and probes of human SUMO deconjugating proteases (SENPs)
Sentrin specific proteases (SENPs) are responsible for activating and deconjugating SUMO (Small Ubiquitin like MOdifier) from target proteins. It remains difficult to study this post-translational modification due to the lack of reagents that can be used to block the removal of SUMO from substrates....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3131534/ https://ncbi.nlm.nih.gov/pubmed/21700208 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.05.008 |
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