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SUMO deconjugation is required for arsenic-triggered ubiquitylation of PML
Acute promyelocytic leukemia is characterized by a chromosomal translocation that produces an oncogenic fusion protein of the retinoic acid receptor α (RARα) and promyelocytic leukemia protein (PML). Arsenic trioxide chemotherapy of this cancer induces the PML moiety to organize nuclear bodies, wher...
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| Izdano u: | Sci Signal |
|---|---|
| Glavni autori: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4603552/ https://ncbi.nlm.nih.gov/pubmed/26060329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scisignal.aaa3929 |
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