Different Roles of 12/15-Lipoxygenase in Diabetic Large and Small Fiber Peripheral and Autonomic Neuropathies

Up-regulation of 12/15-lipoxygenase, which converts arachidonic acid to 12(S)- and 15(S)-hydroxyeicosatetraenoic acids, causes impaired cell signaling, oxidative-nitrosative stress, and inflammation. This study evaluated the role for 12/15-lipoxygenase in diabetic large and small fiber peripheral an...

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Main Authors: Obrosova, Irina G., Stavniichuk, Roman, Drel, Viktor R., Shevalye, Hanna, Vareniuk, Igor, Nadler, Jerry L., Schmidt, Robert. E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Investigative Pathology 2010
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Regular Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928975/
https://ncbi.nlm.nih.gov/pubmed/20724598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100178
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