ROLE OF 12/15-LIPOXYGENASE IN NITROSATIVE STRESS AND PERIPHERAL PREDIABETIC AND DIABETIC NEUROPATHIES

This study evaluated the role for 12/15-lipoxygenase, which converts arachidonic acid to 12(S)- and 15(S)-hydroxyeicosatetraenoic acids, in nitrosative stress in peripheral nervous system and peripheral prediabetic and diabetic neuropathies. The experiments were performed in C57Bl6/J mice made diabe...

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Main Authors: Stavniichuk, Roman, Drel, Viktor R., Shevalye, Hanna, Vareniuk, Igor, Stevens, Martin J., Nadler, Jerry L., Obrosova, Irina G.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056543/
https://ncbi.nlm.nih.gov/pubmed/20599608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.06.016
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