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Ca(2+) release from the sarcoplasmic reticulum is required for sustained TRPM4 activity in cerebral artery smooth muscle cells
The melastatin transient receptor potential (TRP) channel TRPM4 is a critical regulator of vascular smooth muscle cell membrane potential and contractility. Activation of the channel is Ca(2+)-dependent, but prolonged exposure to high (>1 μM) levels of intracellular Ca(2+) causes rapid (within ∼2...
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| Główni autorzy: | , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Physiological Society
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2928641/ https://ncbi.nlm.nih.gov/pubmed/20427713 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00550.2009 |
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