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Endogenous Cytosolic Ca(2+) Buffering is Necessary for TRPM4 Activity in Cerebral Artery Smooth Muscle Cells
The melastatin transient receptor potential (TRP) channel, TRPM4, is a critical regulator of smooth muscle membrane potential and arterial tone. Activation of the channel is Ca(2+)-dependent, but prolonged exposures to high global Ca(2+) causes rapid inactivation under conventional whole-cell patch...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3265659/ https://ncbi.nlm.nih.gov/pubmed/22153976 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2011.11.004 |
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