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Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

Autophagy is an evolutionarily conserved pathway responsible for degradation of cytoplasmic material via the lysosome. Although autophagy has been reported to contribute to cell death, the underlying mechanisms remain largely unknown. In this study, we show that autophagy controls DNA fragmentation...

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Detalhes bibliográficos
Main Authors: Nezis, Ioannis P., Shravage, Bhupendra V., Sagona, Antonia P., Lamark, Trond, Bjørkøy, Geir, Johansen, Terje, Rusten, Tor Erik, Brech, Andreas, Baehrecke, Eric H., Stenmark, Harald
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928014/
https://ncbi.nlm.nih.gov/pubmed/20713604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002035
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