FYCO1 is a Rab7 effector that binds to LC3 and PI3P to mediate microtubule plus end–directed vesicle transport

Autophagy is the main eukaryotic degradation pathway for long-lived proteins, protein aggregates, and cytosolic organelles. Although the protein machinery involved in the biogenesis of autophagic vesicles is well described, very little is known about the mechanism of cytosolic transport of autophago...

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Bibliographic Details
Main Authors: Pankiv, Serhiy, Alemu, Endalkachew A., Brech, Andreas, Bruun, Jack-Ansgar, Lamark, Trond, Øvervatn, Aud, Bjørkøy, Geir, Johansen, Terje
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2010
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812517/
https://ncbi.nlm.nih.gov/pubmed/20100911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200907015
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