NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1

Human ATG8 family proteins (ATG8s) are active in all steps of the macroautophagy pathway, and their lipidation is essential for autophagosome formation. Lipidated ATG8s anchored to the outer surface of the phagophore serve as scaffolds for binding of other core autophagy proteins and various effecto...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:J Biol Chem
Κύριοι συγγραφείς: Shrestha, Birendra Kumar, Skytte Rasmussen, Mads, Abudu, Yakubu Princely, Bruun, Jack-Ansgar, Larsen, Kenneth Bowitz, Alemu, Endalkachew A., Sjøttem, Eva, Lamark, Trond, Johansen, Terje
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Biochemistry and Molecular Biology 2020
Θέματα:
Cell Biology
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996884/
https://ncbi.nlm.nih.gov/pubmed/31857374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010068
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