NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1

Human ATG8 family proteins (ATG8s) are active in all steps of the macroautophagy pathway, and their lipidation is essential for autophagosome formation. Lipidated ATG8s anchored to the outer surface of the phagophore serve as scaffolds for binding of other core autophagy proteins and various effecto...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Shrestha, Birendra Kumar, Skytte Rasmussen, Mads, Abudu, Yakubu Princely, Bruun, Jack-Ansgar, Larsen, Kenneth Bowitz, Alemu, Endalkachew A., Sjøttem, Eva, Lamark, Trond, Johansen, Terje
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996884/
https://ncbi.nlm.nih.gov/pubmed/31857374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010068
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