NIMA-related kinase 9–mediated phosphorylation of the microtubule-associated LC3B protein at Thr-50 suppresses selective autophagy of p62/sequestosome 1

Human ATG8 family proteins (ATG8s) are active in all steps of the macroautophagy pathway, and their lipidation is essential for autophagosome formation. Lipidated ATG8s anchored to the outer surface of the phagophore serve as scaffolds for binding of other core autophagy proteins and various effecto...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Biol Chem
Prif Awduron: Shrestha, Birendra Kumar, Skytte Rasmussen, Mads, Abudu, Yakubu Princely, Bruun, Jack-Ansgar, Larsen, Kenneth Bowitz, Alemu, Endalkachew A., Sjøttem, Eva, Lamark, Trond, Johansen, Terje
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Biochemistry and Molecular Biology 2020
Pynciau:
Cell Biology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6996884/
https://ncbi.nlm.nih.gov/pubmed/31857374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010068
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