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Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during late Drosophila melanogaster oogenesis

Autophagy is an evolutionarily conserved pathway responsible for degradation of cytoplasmic material via the lysosome. Although autophagy has been reported to contribute to cell death, the underlying mechanisms remain largely unknown. In this study, we show that autophagy controls DNA fragmentation...

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Bibliografiske detaljer
Main Authors: Nezis, Ioannis P., Shravage, Bhupendra V., Sagona, Antonia P., Lamark, Trond, Bjørkøy, Geir, Johansen, Terje, Rusten, Tor Erik, Brech, Andreas, Baehrecke, Eric H., Stenmark, Harald
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2928014/
https://ncbi.nlm.nih.gov/pubmed/20713604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201002035
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