Nalaganje...
The Mibefradil Derivative NNC55-0396, a Specific T-Type Calcium Channel Antagonist, Exhibits Less CYP3A4 Inhibition than Mibefradil
A novel mibefradil derivative, NNC55-0396, designed to be hydrolysis resistant was shown to be a selective T-type Ca(2+) channel inhibitor without L-type Ca(2+) channel efficacy. However, its effects on cytochrome P450s have not previously been examined. We investigated the inhibitory effects of NNC...
Shranjeno v:
| Main Authors: | , , , |
|---|---|
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2008
|
| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2927974/ https://ncbi.nlm.nih.gov/pubmed/18411403 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.107.020115 |
| Oznake: |
Označite
Brez oznak, prvi označite!
|