Comparison of mibefradil and derivative NNC 55-0396 effects on behavior, cytochrome P450 activity, and tremor in mouse models of essential tremor

NNC 55-0396 [(1S,2S)-2-(2-(N-[(3-benzimidazol-2-yl)propyl]-N-methylamino)ethyl)-6-fluoro-1,2, 3,4-tetrahydro-1-isopropyl-2-naphtyl cyclopropanecarboxylate dihydrochloride], is a mibefradil derivative that retains potent in vitro T-type calcium channel antagonist efficacy. We compared the two compoun...

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Detaylı Bibliyografya
Asıl Yazarlar: Quesada, Arnulfo, Bui, Peter H., Homanics, Gregg E., Hankinson, Oliver, Handforth, Adrian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3988263/
https://ncbi.nlm.nih.gov/pubmed/21256842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejphar.2011.01.004
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