Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors

Gene therapies that utilize convention-enhanced delivery (CED) will require close monitoring of vector infusion in real time and accurate prediction of drug distribution. The magnetic resonance imaging (MRI) contrast agent, Gadoteridol (Gd), was used to monitor CED infusion and to predict the expres...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Su, Xiaomin, Kells, Adrian P, Aguilar Salegio, Ernesto A, Richardson, R Mark, Hadaczek, Piotr, Beyer, Janine, Bringas, John, Pivirotto, Philip, Forsayeth, John, Bankiewicz, Krystof S
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2010
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927064/
https://ncbi.nlm.nih.gov/pubmed/20551915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.114
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