Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors

Gene therapies that utilize convention-enhanced delivery (CED) will require close monitoring of vector infusion in real time and accurate prediction of drug distribution. The magnetic resonance imaging (MRI) contrast agent, Gadoteridol (Gd), was used to monitor CED infusion and to predict the expres...

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Autores principales: Su, Xiaomin, Kells, Adrian P, Aguilar Salegio, Ernesto A, Richardson, R Mark, Hadaczek, Piotr, Beyer, Janine, Bringas, John, Pivirotto, Philip, Forsayeth, John, Bankiewicz, Krystof S
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2010
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927064/
https://ncbi.nlm.nih.gov/pubmed/20551915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.114
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