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Real-time MR Imaging With Gadoteridol Predicts Distribution of Transgenes After Convection-enhanced Delivery of AAV2 Vectors

Gene therapies that utilize convention-enhanced delivery (CED) will require close monitoring of vector infusion in real time and accurate prediction of drug distribution. The magnetic resonance imaging (MRI) contrast agent, Gadoteridol (Gd), was used to monitor CED infusion and to predict the expres...

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Detalhes bibliográficos
Main Authors: Su, Xiaomin, Kells, Adrian P, Aguilar Salegio, Ernesto A, Richardson, R Mark, Hadaczek, Piotr, Beyer, Janine, Bringas, John, Pivirotto, Philip, Forsayeth, John, Bankiewicz, Krystof S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2927064/
https://ncbi.nlm.nih.gov/pubmed/20551915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.114
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