Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

Polycomb group (PcG) proteins are transcriptional repressors, which regulate proliferation and cell fate decisions during development, and their deregulated expression is a frequent event in human tumours. The Polycomb repressive complex 2 (PRC2) catalyzes trimethylation (me3) of histone H3 lysine 2...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Pasini, Diego, Malatesta, Martina, Jung, Hye Ryung, Walfridsson, Julian, Willer, Anton, Olsson, Linda, Skotte, Julie, Wutz, Anton, Porse, Bo, Jensen, Ole Nørregaard, Helin, Kristian
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Oxford University Press 2010
Θέματα:
Gene Regulation, Chromatin and Epigenetics
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926606/
https://ncbi.nlm.nih.gov/pubmed/20385584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq244
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