Characterization of an antagonistic switch between histone H3 lysine 27 methylation and acetylation in the transcriptional regulation of Polycomb group target genes

Polycomb group (PcG) proteins are transcriptional repressors, which regulate proliferation and cell fate decisions during development, and their deregulated expression is a frequent event in human tumours. The Polycomb repressive complex 2 (PRC2) catalyzes trimethylation (me3) of histone H3 lysine 2...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Pasini, Diego, Malatesta, Martina, Jung, Hye Ryung, Walfridsson, Julian, Willer, Anton, Olsson, Linda, Skotte, Julie, Wutz, Anton, Porse, Bo, Jensen, Ole Nørregaard, Helin, Kristian
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2010
Pynciau:
Gene Regulation, Chromatin and Epigenetics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2926606/
https://ncbi.nlm.nih.gov/pubmed/20385584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq244
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