CC chemokine receptor 4 modulates Toll-like receptor 9-mediated innate immunity and signaling

The present study addressed the modulatory role of CCR4 in TLR9-mediated innate immunity and explored the underlying molecular mechanisms. Our results demonstrated that CCR4-deficient mice were resistant to both septic peritonitis induced by cecal ligation and puncture (CLP) and CpG DNA/D-galactosam...

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Hlavní autoři: Ishii, Makoto, Hogaboam, Cory M., Joshi, Amrita, Ito, Toshihiro, Fong, Daniel J., Kunkel, Steven L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925393/
https://ncbi.nlm.nih.gov/pubmed/18624303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838360
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