Toll-like Receptor 9 Activation Is a Key Mechanism for the Maintenance of Chronic Lung Inflammation

Rationale: Accumulating evidence supports the hypothesis that the continuous host response to a persistent challenge can polarize the cytokine environment toward a Th2 cytokine phenotype, but the mechanisms responsible for this skewing are not clear. Objectives: We investigated the role of Toll-like...

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Bibliographic Details
Main Authors: Ito, Toshihiro, Schaller, Matthew, Raymond, Tracy, Joshi, Amrita D., Coelho, Ana L., Frantz, Fabiani G., Carson, William F., Hogaboam, Cory M., Lukacs, Nicholas W., Standiford, Theodore J., Phan, Sem H., Chensue, Stephen W., Kunkel, Steven L.
Format: Artigo
Language:Inglês
Published: American Thoracic Society 2009
Subjects:
E. Interstitial Lung Disease
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2796734/
https://ncbi.nlm.nih.gov/pubmed/19797157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.200906-0892OC
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