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Toll-Like Receptor 9 Modulates Immune Responses to Aspergillus fumigatus Conidia in Immunodeficient and Allergic Mice

The role of Toll-like receptor 9 (TLR9) in antifungal responses in the immunodeficient and allergic host is unclear. We investigated the role of TLR9 in murine models of invasive aspergillosis and fungal asthma. Neutrophil-depleted TLR9 wild-type (TLR9(+/+)) and TLR9-deficient (TLR9(−/−)) mice were...

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Detalhes bibliográficos
Main Authors: Ramaprakash, Hemanth, Ito, Toshihiro, Standiford, Theodore J., Kunkel, Steven L., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2612288/
https://ncbi.nlm.nih.gov/pubmed/18936185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00998-08
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