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Toll Like Receptor 3 modulates immunopathology during a Schistosoma mansoni egg-driven Th2 response in the lung

We examined the role of Toll Like Receptor 3 (TLR3) in Th2-driven pulmonary granulomatous disease, using wildtype (TLR3(+/+)) and TLR3 gene deficient (TLR3(−/−)) mice in a well-established model of S. mansoni egg induced pulmonary granuloma. The intravenous bolus injection of S. mansoni eggs into S....

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Detalhes bibliográficos
Publicado no:Eur J Immunol
Main Authors: Joshi, Amrita D., Schaller, Matthew, Lukacs, Nicholas W., Kunkel, Steven L., Hogaboam, Cory M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5382867/
https://ncbi.nlm.nih.gov/pubmed/19009529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.200838629
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