Interleukin-13 Fusion Cytotoxin Arrests Schistosoma mansoni Egg-Induced Pulmonary Granuloma Formation in Mice

Schistosoma mansoni egg-induced lung pathology requires the actions of interleukin (IL)-4 and IL-13. Because receptors for IL-4 and IL-13 share chains, we examined the effect of a fusion protein comprised of IL-13 and Pseudomonas exotoxin (IL13-PE) on the development of pulmonary granulomas in mice....

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Hauptverfasser: Jakubzick, Claudia, Kunkel, Steven L., Joshi, Bharat H., Puri, Raj K., Hogaboam, Cory M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2002
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1867284/
https://ncbi.nlm.nih.gov/pubmed/12368202
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