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TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4

TLR9 activation is important for the maintenance of mycobacteria-elicited pulmonary granulomatous responses, hallmarks of protective immune responses following mycobacterial infection. However, the mechanism or mechanisms underlying this effect of TLR9 are not clear. Here, we show that Tlr9-deficien...

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Autors principals: Ito, Toshihiro, Schaller, Matthew, Hogaboam, Cory M., Standiford, Theodore J., Sandor, Matyas, Lukacs, Nicholas W., Chensue, Stephen W., Kunkel, Steven L.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Clinical Investigation 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613456/
https://ncbi.nlm.nih.gov/pubmed/19075396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI35647
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