Delta-Like 4 Differentially Regulates Murine CD4(+) T Cell Expansion via BMI1

BACKGROUND: Studies have shown that Notch is essential for the maintenance of a T cell Th2 phenotype in vivo. It has also been shown that Notch ligands have diverse functions during T cell activation. We chose to investigate the role of Notch ligands during the Th2 response. PRINCIPAL FINDINGS: We s...

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Main Authors: Schaller, Matthew A., Logue, Hannah, Mukherjee, Sumanta, Lindell, Dennis M., Coelho, Ana Lucia, Lincoln, Pamela, Carson, William F., Ito, Toshihiro, Cavassani, Karen A., Chensue, Stephen W., Hogaboam, Cory M., Lukacs, Nicholas W., Kunkel, Steven L.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923143/
https://ncbi.nlm.nih.gov/pubmed/20808960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012172
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