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Staging of Alzheimer's Pathology in Triple Transgenic Mice: A Light and Electron Microscopic Analysis
The age-related pathological cascade underlying intraneuronal tau formation in 3xTg-AD mice, which harbor the human APP(Swe), PS1(M126V) , and Tau(P301L) gene mutations, remains unclear. At 3 weeks of age, AT180, Alz50, MC1, AT8, and PHF-1 intraneuronal immunoreactivity appeared in the amygdala and...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE-Hindawi Access to Research
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2925282/ https://ncbi.nlm.nih.gov/pubmed/20798886 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/780102 |
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