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Robust light–dark patterns and reduced amyloid load in an Alzheimer’s disease transgenic mouse model
Circadian disruption resulting from exposure to irregular light–dark patterns and sleep deprivation has been associated with beta amyloid peptide (Aβ) aggregation, which is a major event in Alzheimer’s disease (AD) pathology. We exposed 5XFAD mice and littermate controls to dim-light vs. bright-ligh...
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| Publicado no: | Sci Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7351709/ https://ncbi.nlm.nih.gov/pubmed/32651420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-68199-5 |
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