Preclinical Evaluation of an Anti-CD25 Monoclonal Antibody, 7G7/B6, Armed with the β-Emitter, Yttrium-90, as a Radioimmunotherapeutic Agent for Treating Lymphoma

OBJECTIVE: Radioimmunotherapy of cancer with radiolabeled antibodies has shown promise. We evaluated an anti-CD25 monoclonal Antibody, 7G7/B6, armed with (90)Y as a potential radioimmunotherapeutic agent for CD25-expressing lymphomas. MATERIALS AND METHODS: The lymphoma model was established by subc...

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Main Authors: Zhang, Meili, Yao, Zhengsheng, Garmestani, Kayhan, Yu, Sarah, Goldman, Carolyn K., Paik, Chang H., Brechbiel, Martin W., Carrasquillo, Jorge A., Waldmann, Thomas A.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2009
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2925030/
https://ncbi.nlm.nih.gov/pubmed/19538052
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2008.0577
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