Effective therapy for a murine model of human anaplastic large-cell lymphoma with the anti-CD30 monoclonal antibody, HeFi-1, does not require activating Fc receptors

CD30 is a member of the tumor necrosis factor receptor family. Overexpression of CD30 on some neoplasms versus its limited expression on normal tissues makes this receptor a promising target for antibody-based therapy. Anaplastic large-cell lymphoma (ALCL) represents a heterogeneous group of aggress...

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Bibliographische Detailangaben
Hauptverfasser: Zhang, Meili, Yao, Zhengsheng, Zhang, Zhuo, Garmestani, Kayhan, Goldman, Carolyn K., Ravetch, Jeffrey V., Janik, John, Brechbiel, Martin W., Waldmann, Thomas A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society of Hematology 2006
Schlagworte:
Neoplasia
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1895489/
https://ncbi.nlm.nih.gov/pubmed/16551968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2005-11-4607
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