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Preclinical evaluation of a monoclonal antibody targeting the epidermal growth factor receptor as a radioimmunodiagnostic and radioimmunotherapeutic agent

BACKGROUND AND PURPOSE: The studies described here are the first to evaluate the in vitro and in vivo properties of (111)In-CHX-A″-panitumumab for radioimmunotherapy (α- and β(-)-emitters) and radioimmunoimaging (single photon emission computed tomography and positron emission tomography). EXPERIMEN...

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Detalhes bibliográficos
Main Authors: Ray, GL, Baidoo, KE, Wong, KJ, Williams, M, Garmestani, K, Brechbiel, MW, Milenic, DE
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2765311/
https://ncbi.nlm.nih.gov/pubmed/19681874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2009.00327.x
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