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Cetuximab: Preclinical Evaluation of a Monoclonal Antibody Targeting EGFR for Radioimmunodiagnostic and Radioimmunotherapeutic Applications

The monoclonal antibody, cetuximab, binds to epidermal growth-factor receptor and thus provides an opportunity to create both imaging and therapies that target this receptor. The potential of cetuximab as a radioimmunoconjugate, using the acyclic bifunctional chelator, CHX-A″-DTPA, was investigated....

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Detalhes bibliográficos
Main Authors: Milenic, Diane E., Wong, Karen J., Baidoo, Kwamena E., Ray, Geoffrey L., Garmestani, Kayhan, Williams, Mark, Brechbiel, Martin W.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2586878/
https://ncbi.nlm.nih.gov/pubmed/18999934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/cbr.2008.0493
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