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Small-molecule suppressors of cytokine-induced beta-cell apoptosis

Pancreatic beta-cell apoptosis is a critical event during the development of type-1 diabetes. The identification of small molecules capable of preventing cytokine-induced apoptosis could lead to avenues for therapeutic intervention. We developed a set of phenotypic cell-based assays designed to iden...

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Détails bibliographiques
Auteurs principaux: Chou, Danny Hung-Chieh, Bodycombe, Nicole E., Carrinski, Hyman A., Lewis, Timothy A., Clemons, Paul A., Schreiber, Stuart L., Wagner, Bridget K.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2924935/
https://ncbi.nlm.nih.gov/pubmed/20550176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb100129d
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