Synthesis of a Novel Suppressor of β-Cell Apoptosis via Diversity-Oriented Synthesis

[Image: see text] The synthesis of a stereochemically diverse library of medium-sized rings accessible via a “build/couple/pair” strategy is described. Key aspects of the synthesis include S(N)Ar cycloetherification of a linear amine template to afford eight stereoisomeric eight-membered lactams and...

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Egile Nagusiak: Chou, Danny Hung-Chieh, Duvall, Jeremy R., Gerard, Baudouin, Liu, Haibo, Pandya, Bhaumik A., Suh, Byung-Chul, Forbeck, Erin M., Faloon, Patrick, Wagner, Bridget K., Marcaurelle, Lisa A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Chemical Society 2011
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3171963/
https://ncbi.nlm.nih.gov/pubmed/21927648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200120m
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