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Small molecules of different origins have distinct distributions of structural complexity that correlate with protein-binding profiles
Using a diverse collection of small molecules generated from a variety of sources, we measured protein-binding activities of each individual compound against each of 100 diverse (sequence-unrelated) proteins using small-molecule microarrays. We also analyzed structural features, including complexity...
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| Main Authors: | , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2973913/ https://ncbi.nlm.nih.gov/pubmed/20956335 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012741107 |
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