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Connecting Small Molecules with Similar Assay Performance Profiles Leads to New Biological Hypotheses
High-throughput screening allows rapid identification of new candidate compounds for biological probe or drug development. Here, we describe a principled method to generate “assay performance profiles” for individual compounds that can serve as a basis for similarity searches and cluster analyses. O...
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| Publicat a: | J Biomol Screen |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5554958/ https://ncbi.nlm.nih.gov/pubmed/24464433 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1087057113520226 |
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