cPLA(2) Is Protective Against COX Inhibitor–Induced Intestinal Damage

Cytosolic phospholipase A(2) (cPLA(2)) is the rate-limiting enzyme responsible for the generation of prostaglandins (PGs), which are bioactive lipids that play critical roles in maintaining gastrointestinal (GI) homeostasis. There has been a long-standing association between administration of cycloo...

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Bibliografske podrobnosti
Main Authors: Montrose, David C., Kadaveru, Krishna, Ilsley, Jillian N. M., Root, Sierra H., Rajan, Thiruchanduri V., Ramesh, Manish, Nichols, Frank C., Liang, Bruce T., Sonin, Dmitry, Hand, Arthur R., Zarini, Simona, Murphy, Robert C., Belinsky, Glenn S., Nakanishi, Masako, Rosenberg, Daniel W.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2010
Teme:
Molecular Toxicology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2923287/
https://ncbi.nlm.nih.gov/pubmed/20562220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/toxsci/kfq184
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