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Modulation of the activity of cytosolic phospholipase A2α (cPLA2α) by cellular sphingolipids and inhibition of cPLA2α by sphingomyelin

We examined the effect of the cellular sphingolipid level on the release of arachidonic acid (AA) and activity of cytosolic phospholipase A2α (cPLA2α) using two Chinese hamster ovary (CHO)-K1-derived mutants deficient in sphingolipid synthesis: LY-B cells defective in the LCB1 subunit of serine palm...

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Bibliografski detalji
Glavni autori: Nakamura, Hiroyuki, Wakita, Shigeo, Suganami, Akiko, Tamura, Yutaka, Hanada, Kentaro, Murayama, Toshihiko
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Biochemistry and Molecular Biology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2842140/
https://ncbi.nlm.nih.gov/pubmed/19965591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M002428
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